Research at Leeds Beckett
Professor Clive Beggs
About Professor Clive Beggs
Clive Beggs is Professor of Applied Physiology at Leeds Beckett University and adjunct Professor of Neurology in the medical school at the University at Buffalo, State University of New York. He is both a Physiologist (Member of the Physiological Society) and a Bio-Engineer (Fellow of the Institution of Mechanical Engineers; Fellow of the Society of Biology; and Fellow of the Royal Society of Medicine) who holds PhDs in two disciplines and specializes in the use of advanced statistical and numerical modelling techniques to interpret complex physiological and clinical systems. Professor Beggs specializes in inter-disciplinary research and has for many years worked at the interface between medicine, physics and mathematics, working with clinical teams in Leeds, Bradford and Buffalo. Prior to joining Leeds Beckett University, he was Professor of Medical Engineering at the University of Bradford (2005-2015), and before that he was Senior Lecturer in Aerobiological Engineering at the University of Leeds (1996-2005).
Professor Beggs' main areas of research are in vascular haemodynamics; intracranial biomechanics; neurological disease; and biofluids (including lymphatics and tissue micro-circulation). In recent years he has been involved in projects working on multiple sclerosis, Alzheimer's disease, and vascular changes associated with aging, with a variety of clinical partners in the USA, Italy and Taiwan. Professor Beggs' other research interest is the use of mathematical/computer models to interpret complex systems. With regard to this, he is currently working on a wide variety of projects ranging from biomechanics to talent identification in young rugby players.
Professor Beggs is currently working on the following research projects:
- Characterising the dynamic behaviour of the fluids in the cranium: The transient behaviour of the intracranial arterial, venous, and cerebrospinal fluid (CSF) flow is poorly understood. This project uses magnetic resonance imaging (MRI) to characterise the dynamic behaviour of the intracranial fluids in healthy individuals, with the aim of better understanding how these fluids interact with each other. The information delivered by the project will yield new insights into the physiology of the brain, which should greatly benefit researchers investigating both hydrocephalus and dementia. [Principal collaborators: Dr Marcella Lagana (Fondazione Don Carlo Gnocchi, Milan, Italy); Professor Simon Shepherd (University of Bradford)]
- Intracranial biomechanical changes associated with multiple sclerosis: In healthy individuals there is a biomechanical link between CSF motion in the cranium and cerebral venous drainage. This project investigates whether or not this relationship is altered in patients with multiple sclerosis (MS). The information delivered by the project should yield new insights into pathophysiological changes that occur in the neurovascular system of MS patients, which should be of benefit to all researchers working in the field. [Principal collaborators: Professor Robert Zivadinov (University of Buffalo, USA)]
- Sweat and blood electrolyte changes during exercise: Changes in blood electrolytes arising from exercise are normally determined through blood samples taken before and after exercise. This project investigates the potential of using changes in sweat electrolytes as a surrogate for changes in blood chemistry arising from exercise. [Principal collaborators: Professor Rod King and Dr Ben Jones (Leeds Beckett University)]
- Development of a higher-dimensional model for use in the talent identification of athletes: There is currently considerable interest in early-stage identification of future professional athletes. This project uses advanced orthogonal techniques to analyse multivariate performance data, with the aim of identifying future professional athletes. [Principal collaborators: Dr Kevin Till and Dr Ben Jones (Leeds Beckett University)]