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Professor David Woods

Professor

David is a Consultant Endocrinologist in the Defence Medical Services, Reader in Military Medicine and Professor of Sport and Exercise Endocrinology, Leeds Beckett University.

David's research interests focus on the interaction of the human with the environment, particularly in relation to exercise under hypoxic or thermal stress. Recent research strategies have included an investigation of the endocrine, cardiac and physiological response to normobaric and hypobaric hypoxia. Recent field studies in Nepal, Bolivia and the Alps have examined subjects suffering acute mountain sickness or high pulmonary artery systolic pressure and identified brain natriuretic peptide as a potential biomarker. These studies are complimented by laboratory based studies in the hypobaric chamber at the Centre for Aviation Medicine, RAF Henlow and the normobaric hypoxic chamber here in Leeds. Future work will build on these themes and in particular investigate pre-acclimatization strategies.

Research in the field of thermal stress has four major strands: the assessment of the effect of heat and physical exercise on the gonadotrophic axis and spermatogenesis; investigation of the thermal burden of exercise for the soldier in a hot environment; investigating hyponatraemic heat illness in collaboration with the Institute of Naval Medicine and the search for a biomarker for thermal stress.

Research Interests

David's research strategy aims to mitigate the effects of environmental stressors such as hypoxia and thermal stress in order to minimise morbidity and maximise performance for both the deployed soldier and civilian alike.

Carnegie School of Sport

Selected Outputs

Gifford RM; Reynolds RM; Greeves J; Anderson RA; Woods D (In press) Reproductive dysfunction and associated pathology in women undergoing military training. Journal of the Royal Army Medical Corps, 163 (5),

https://doi.org/10.1136/jramc-2016-000727
Woods D; Hill NE; Neely RDG; Talks KL; Heggie A; Quinton R (2017) Haematopoiesis shows closer correlation with calculated free testosterone in men than total testosterone. The Journal of Applied Laboratory Medicine, 1 (4), pp. 441-444.

https://doi.org/10.1373/jalm.2016.022012
Mackey J; Mellor A; Watchorn J; Burnett A; Boot C; Woods D (2016) The adrenocortical response to synthetic ACTH following a trek to high altitude. Hormone and Metabolic Research, 48 (10), pp. 658-663.

https://doi.org/10.1055/s-0042-112816
Shannon O; Duckworth L; Barlow M; Woods D; Lara J; Siervo M; O'Hara J (2016) Dietary nitrate supplementation enhances high-intensity running performance in moderate normobaric hypoxia, independent of aerobic fitness. Nitric Oxide, 59 pp. 63-70.

https://doi.org/10.1016/j.niox.2016.08.001
Shannon O; Barlow M; Duckworth L; Woods D; Griffiths A; Grindrod A; O'Hara J (2016) The reliability of a pre-loaded treadmill time-trial in moderate normobaric hypoxia. International Journal of Sports Medicine, 37 (10), pp. 825-830.

https://doi.org/10.1055/s-0042-108651
Boos C; O'Hara J; Mellor A; Hodkinson PD; Tsakirides C; Reeve N; Gallagher L; Green ND; Woods DR (2016) A Four-Way Comparison of Cardiac Function with Normobaric Normoxia, Normobaric Hypoxia, Hypobaric Hypoxia and Genuine High Altitude. PLoS One, 11 (4),

https://doi.org/10.1371/journal.pone.0152868
Boos C; Mellor A; O'Hara J; Tsakirides C; Woods DR (2016) The Effects of Sex on Cardiopulmonary Responses to Acute Normobaric Hypoxia. High Altitude Medicine and Biology, 17 (2), pp. 108-115.

https://doi.org/10.1089/ham.2015.0114
Boos CJ; Woods DR; Varias A; Biscocho S; Heseltine P; Mellor AJ (2016) High Altitude and Acute Mountain Sickness and Changes in Circulating Endothelin-1, Interleukin-6, and Interleukin-17a. High Altitude Medicine & Biology, 17 (1), pp. 25-31.

https://doi.org/10.1089/ham.2015.0098
Lois KB; Santhakumar A; Vaikkakara S; Mathew S; Long A; Johnson SJ; Peaston R; Neely RDG; Richardson DL; Graham J (2016) Phaeochromocytoma and <scp>ACTH</scp>‐dependent cushing's syndrome: tumour crf secretion can mimic pituitary cushing's disease. Clinical Endocrinology, 84 (2), pp. 177-184.

https://doi.org/10.1111/cen.12960
Boos C; Bakker-Dyos J; Watchorn J; Woods DR; O'Hara J; Macconnachie L; Mellor A (2016) A comparison of two methods of heart rate variability assessment at high altitude. Clinical physiology and functional imaging, 37 pp. 582-587.

https://doi.org/10.1111/cpf.12334
Hazlerigg A; Woods DR; Mellor AJ (2015) Incidence of acute mountain sickness in UK Military Personnel on Mount Kenya. J R Army Med Corps

https://doi.org/10.1136/jramc-2015-000524
Moore AC; Stacey MJ; Bailey KG; Bunn RJ; Woods DR; Haworth KJ; Brett SJ; Folkes SE (2015) Risk factors for heat illness among British soldiers in the hot Collective Training Environment. J R Army Med Corps

https://doi.org/10.1136/jramc-2015-000427
Hill NE; Woods DR; Delves SK; Murphy KG; Davison AS; Brett SJ; Quinton R; Turner S; Stacey M; Allsopp AJ (2015) The gonadotrophic response of Royal Marines during an operational deployment in Afghanistan. Andrology, 3 (2), pp. 293-297.

https://doi.org/10.1111/andr.308
Woods DR; Delves SK; Britland SE; Shaw A; Brown PE; Bentley C; Hornby S; Burnett A; Lanham-New SA; Fallowfield JL (2015) Nutritional status and the gonadotrophic response to a polar expedition. Appl Physiol Nutr Metab, 40 (3), pp. 292-297.

https://doi.org/10.1139/apnm-2014-0418
Mellor AJ; Boos CJ; Ball S; Burnett A; Pattman S; Redpath M; Woods DR (2015) Copeptin and arginine vasopressin at high altitude: relationship to plasma osmolality and perceived exertion. European Journal of Applied Physiology, 115 (1), pp. 91-98.

https://doi.org/10.1007/s00421-014-2994-7
Boos CJ; Holdsworth DA; Hall DP; Mellor A; O'Hara J; Woods DR (2014) Comparison of two methods of assessing total body water at sea level and increasing high altitude. Clinical Physiology and Functional Imaging, 34 (6), pp. 478-484.

https://doi.org/10.1111/cpf.12121
Mellor A; Woods D (2014) Physiology studies at high altitude; why and how. Journal of the Royal Army Medical Corps, 160 (2), pp. 131-134.

https://doi.org/10.1136/jramc-2013-000206
Mellor A; Boos C; Holdsworth D; Begley J; Hall D; Lumley A; Burnett A; Hawkins A; O'Hara JP; Ball S (2014) Cardiac biomarkers at high altitude. High Altitude Medicine and Biology
Mellor AJ; Woods DR; O'Hara JP; Howley M; Watchorn J; Boos C (2014) Rating of Perceived Exertion and Acute Mountain Sickness during a High Altitude Trek. Aviation, Space, and Environmental Medicine
Boos CJ; Holdsworth DA; Hall DP; Mellor A; O'Hara J; Woods DR (2014) Comparison of two methods of assessing total body water at sea level and increasing high altitude. Clinical Physiology and Functional Imaging, 34 (6), pp. 478-484.

https://doi.org/10.1111/cpf.12121
Woods DR; Mellor A; Begley J; Stacey M; O'Hara J; Hawkins A; Yarker J; Foxen S; Smith C; Boos C (2013) Brain natriuretic peptide and NT-proBNP levels reflect pulmonary artery systolic pressure in trekkers at high altitude. Physiological research / Academia Scientiarum Bohemoslovaca, 62 (6), pp. 597-603.
Mellor A; Boos C; Stacey M; Hooper T; Smith C; Begley J; Yarker J; Piper R; O'Hara J; King R (2013) Neutrophil gelatinase-associated lipocalin: its response to hypoxia and association with acute mountain sickness. Disease markers, 35 (5), pp. 537-542.

https://doi.org/10.1155/2013/601214