Nanoparticle technologies for membrane protein research
27-28 June 2017
Leeds Beckett University
Detergents have traditionally provided a solution to the problem of solvating membrane proteins, but in recent years there has been a growing trend for isolating membrane proteins as nanoparticles. Stable bilayer segments, bicelles, were quickly followed by the development of amphipathic polymers (amphipols). Thereafter, amphipathic proteins were used to create self-assembling lipid nanodiscs, in which membrane proteins were reinserted into small discs of lipid bilayers. The most recent innovations, SMALPs and lipodiscs combine these ideas by directly solubilising biological membranes to produce membrane protein/lipid nanoparticles. Together, these methods overcome many of the difficulties faced by membrane protein biochemists and offer enormous opportunities to rapidly deepen and broaden our understanding of these important proteins.
The aim of this meeting is to bring together researchers from academia and industry with interest and expertise in these different methodologies, who are united in the goal of elucidating the structures and functions of membrane proteins.
(registration includes conference fee, lunches, refreshments and BBQ):
Student/PhD – £30.00
Other academic/Industry – £120.00
Deadline for registration is 1 June 2017
Plenary speaker: Steve Sligar
Confirmed speakers: Tim Dafforn, Sandro Keller, Bonnie Wallace, Tony Watts
Talk and poster abstract submission
Talk and poster abstract submission – deadline is 15 May 2017.
Successful talks and posters will be notified by 23 May.