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Dr Carine De Marcos Lousa

About Dr Carine De Marcos Lousa

Dr Carine De Marcos Lousa joined Leeds Beckett University in October 2015. Her research interests focus on Biochemistry and Cell Biology.

Carine has been worked in the University of Leeds (2006-2015), and in the University of Crete (2003-2006). She has a PhD in Biochemistry and Cell Biology (in Health Sciences) from the University of Bordeaux 2 (France). Dr De Marcos Lousa has extensive research experience in Organelle Biochemistry linked to Pathologies.

Carine also has taught Biochemistry and Cell biology in various Universities such as the University of Bordeaux, where she held a one year teaching and research position, and the University of Leeds, before starting to teach in Leeds Beckett University.

Current Teaching

Carine teaches the following modules on our BSc Biomedical Sciences courses:

  • Level 4:
    • Biochemistry
    • Introduction to Biomedical Sciences
    • Cellular Biology, Haematology and Immunology
  • Level 5:
    • Professional Scientific Practice
    • Research Investigations
  • Level 6:
    • Clinical Biochemistry
    • Contemporary Issues

And the following modules on out MSc Toxicological Sciences, MSc Microbiology and Biotechnology, and MSc Applied Biomedical Sciences Research:

  • Bioanalytical Techniques
  • Research Project

Research Interests

Dr De Marcos Lousa's research interests focus on using Models such as yeast and plants, to understand the molecular mechanisms involved in pathologies. Previously, Dr De Marcos Lousa has characterised the functional difference between the three human isoforms of the ADP/ATP carrier using the baker's yeast model. She has identified the effect of specific mutations involved in Cardiomyopathies. More recently, Dr De Marcos Lousa has been working on the plant peroxisomal ABC transporter, an homologous of human ALDP1 involved in adrenoleukodystrophy. Her work has allowed for the first time the identification of a third enzymatic activity in a ABC transporter. Before moving to Leeds Beckett University, Dr De Marcos Lousa was studying vacuolar trafficking in plants, which is essential for food crop improvement and biofuel technology.

Dr De Marcos Lousa's current research is focusing on Nanomedicine. Using a variety of techniques including molecular biology, Biochemistry, Cell Biology and Cell Culture, Dr De Marcos Lousa is exploring new ways to engineer nanoparticles for targeted drug delivery.

Selected Publications

Journal articles (3)

  • Sansebastiano GPD; Barozzi F; Piro G; Denecke J; Lousa CDM (2017) Trafficking routes to the plant vacuole: Connecting alternative and classical pathways
  • Gershlick DC; De Marcos Lousa C; Foresti O; Lee AJ; Pereira EA; daSilva LLP; Bottanelli F; Denecke J (2014) Golgi-dependent transport of vacuolar sorting receptors is regulated by COPII, AP1, and AP4 protein complexes in tobacco
  • Lousa CDM; van Roermund CWT; Postis VLG; Dietrich D; Kerr ID; Wanders RJA; Baldwin SA; Baker A; Theodoulou FL (2013) Intrinsic acyl-CoA thioesterase activity of a peroxisomal ATP binding cassette transporter is required for transport and metabolism of fatty acids
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