Interdisciplinary Centre for Implant Research (IRIS)
Spearheading interdisciplinary research into the provision and use of medical implants and devices to promote patient safety and quality of care, and to examine how implants impact being human.
IRIS is the only research centre of its kind that aims to map, interrogate and illuminate the field of medical implants, connecting multidisciplinary researchers in this area. Medical implants are devices that are inserted into the human body to replace, support or augment an existing biological structure, for medical and/or cosmetic reasons. Focusing primarily on high-risk, paused and banned products, IRIS provides critical, evidence-based insights on controversial implants such as breast implants, surgical mesh, and metal-on-metal hip implants. It also serves as a ready-made, expert unit that can mobilise quickly to respond to urgent, unanticipated and emerging implant-related issues.
Working with existing national and international collaborators, interdisciplinary researchers at IRIS are investigating developments and interventions relating to medical implants across three key themes:
- Health and wellbeing impacts upon patients and consumers, including how shifting policies and clinical practices affect patient and consumer behaviour, decision-making and patient-reported outcomes
- Social and psychological impacts on identities, relationships and inequalities (e.g. concerning gender, class, and race)
- Political and criminology issues in relation to regulation and reports of patient harm
Future work at IRIS aims to include:
- Ethical debates, legal frameworks and regulatory norms, practices and policies
- Industrial manufacture and promotion of medtech devices for diverse markets
- Posthumanist futures implied by the globalisation of medical implant technologies and their incorporation into everyday life
- Bioscientific, laboratory-based evidence and its integration and dissemination within wider clinical, regulatory, manufacturing and commercial implant practices
Professor Georgina Jones
Georgina Jones is a Professor of Health Psychology and Chartered Psychologist. Her research uses both quantitative and qualitative research methods and focuses on quality-of-life measurement, psychometrics, decision-making and questionnaire development, with a special focus on women's reproductive health.
Professor Brendan Gough
Brendan Gough is a professor of social psychology and Director of Research at the School of Humanities and Social Sciences. He is a qualitative researcher, specializing in men’s health.
Dr Bhupinder Sharma
Dr Sharma is a recognised UK authority on lymphoma imaging, and invited co-author of the UK MHRA BIA-ALCL Guidelines. He provides clinical medical and imaging BIA-ALCL expertise, driving forward original research publications with the IRIS team.
Professor Lynda Wyld
Lynda Wyld is a professor of Surgical Oncology at the University of Sheffield and honorary Consultant Oncoplastic Breast Surgeon at Doncaster and Bassetlaw Teaching Hospitals NHS Foundation Trust. Professor Wyld brings expertise in oncoplastic breast surgery, evidence-based medicine, quality of life, and older patients with cancer.
Professor Anand Deva
Anand Deva is Professor of Plastic and Reconstructive Surgery at Macquarie University, Sydney, Australia. His role is to continue to develop better safety around breast implants through research and to empower women to make informed choices.
Professor Ruth Robbins
Ruth Robbins is Professor of English Literature and Director of Research for Humanities in the School of Humanities and Social Sciences. Her role in IRIS is to bring insights from her expertise in the histories and representations of health in the medical humanities.
Professor Mark Johnson
Mark Johnson is Professor of Pain and Analgesia in the School of Health. He investigates the science of pain and its management with specific interest in therapeutic neuromodulation, e.g. spinal cord stimulation. He has expertise in the design and delivery of clinical trials, laboratory studies on healthy humans, and evidence syntheses.
Professor Alicia O’Cathain
Alicia O'Cathain is Professor of Health Services Research at ScHARR, University of Sheffield, bringing expertise in mixed methods research and leading the qualitative research of the APPRAISE project.
Professor Richard M Hall
Professor Richard M Hall undertakes research in medical devices and biomechanics particularly of articulating joints and the spine. Within this domain he has succeeded in developing and provide leadership for several large national and international collaborative research projects that cut across disciplines and bring together leading academics, clinicians, patients and industrial innovators.
Research at IRIS is undertaken in collaboration with partners from a range of disciplines and interdisciplinary fields, from medicine to sociology, gender studies to medical ethics and law, technology to toxicology.
- Professor Nik Brown (Professor of Sociology - University of York)
- Professor Marie-Andree Jacob (Professor of Law - University of Leeds)
- Professor Dr Jan Willem Cohen Tervaert (Professor of Immunology - University of Alberta, Canada)
- James Cook (Breast Implant Victim Advocacy, Texas, USA)
- Nicole Daruda (Founder of Breast Implant Illness and Healing, and Director of the Healing Breast Implant Illness Society, North America)
- Dr Henry Dijkman (HAN University of Applied Sciences, Netherlands)
- Professor Fabio Santanelli di Pompeo (Professor in Plastic Surgery, Sapienza University, Rome Italy)
- Erick Vogelenzang (President, Patient Advocacy)
A Patient-reported outcome measure for PRolApse, Incontinence and meSh complication surgery (APPRAISE) is a three-year National Institute of Health Research (NIHR) funded study to understand the lived experience of prolapse, incontinence and mesh complication surgery.
Breast implant removal
You are invited to participate in a study focusing on adverse events related to breast implants. Adverse events are issues such as capsular contracture, BIA-ALCL, rupture and breast implant illness. The purpose of the study is to better understand the relationship between implants, infection and BIA-ALCL, as well as the association of breast implants and systemic symptoms termed Breast Implant Illness.
Breast implant removal
- Sharma K, Gilmour A, Jones G, O’Donoghue JM (2022). A descriptive systematic review of outcomes following the treatment of breast implant associated anapaestic large cell lymphoma (BIA-ALCL). Submitted to JPRAS Open (The Journal of Plastic, Reconstructive & Aesthetic Surgery (14th May 2022).
- Staniford LJ, Gough B, Ashley, L, Wyld L, Sharma, K, Deva, A, Sharma, B, Jones GL. What psycho-social issues are reported by women who are concerned about or diagnosed with breast implant-associated anaplastic large cell lymphoma (BIA-ALCL)?: a systematic review. Completed and manuscript in preparation for submission to Psycho-Oncology.